Infection-relevant conditions dictate differential versus coordinate expression of Salmonella chaperones and cochaperones
Chan C, Mukai K, Groisman E. Infection-relevant conditions dictate differential versus coordinate expression of Salmonella chaperones and cochaperones. MBio 2025, 16: e00227-25. PMID: 40162747, PMCID: PMC12077118, DOI: 10.1128/mbio.00227-25.Peer-Reviewed Original ResearchConceptsInfection-relevant conditionsJ-domainProtein homeostasisChaperone DnaKCytoplasmic MgMolecular chaperonesNucleotide exchange factor GrpEChaperone trigger factorSigma factor RpoHProteins co-translationallyExpression of molecular chaperonesPreventing protein aggregationIncreased mRNA amountsPerturb protein homeostasisMRNA amountsCochaperone DnaJRpoH proteinCo-translationallyPost-translationallyCochaperoneExpressed genesFolded proteinsDnaKCoordinated expressionChaperone
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