PTPN22 +788 G>A (R263Q) Polymorphism is Associated with mRNA Expression but it is not a Susceptibility Marker for Rheumatoid Arthritis Patients from Western Mexico
Ramírez-Pérez S, Sánchez-Zuno G, Chavarría-Buenrostro L, Montoya-Buelna M, Reyes-Pérez I, Ramírez-Dueñas M, Palafox-Sánchez C, Martínez-Bonilla G, Muñoz-Valle J. PTPN22 +788 G>A (R263Q) Polymorphism is Associated with mRNA Expression but it is not a Susceptibility Marker for Rheumatoid Arthritis Patients from Western Mexico. Biochemical Genetics 2019, 57: 455-465. PMID: 30637604, DOI: 10.1007/s10528-019-09902-8.Peer-Reviewed Original ResearchConceptsWestern Mexican populationPolymerase chain reaction-restriction fragment length polymorphismRA patientsControl subjectsMRNA expressionG/A genotypeRA susceptibilityReal-time quantitative-PCR assayAssociated with RA susceptibilityRheumatoid arthritisMexican populationReaction-restriction fragment length polymorphismHomozygous G/G genotypeAssociated with mRNA expressionCase-control studyNon-HLA genesAssociated with rheumatoid arthritisRheumatoid arthritis patientsG/G genotypeSusceptibility markersCaucasian populationPatientsPTPN22Quantitative-PCR assayRA risk
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