2023
3D hepatic organoid production from human pluripotent stem cells
Jin Z, Xu K, Kim J, Guo H, Yao X, Xu Y, Li Y, Ryu D, Kim K, Hong K, Kim Y, Wang L, Cao Q, Kim K, Kim N, Han D. 3D hepatic organoid production from human pluripotent stem cells. Differentiation 2023, 135: 100742. PMID: 38104501, DOI: 10.1016/j.diff.2023.100742.Peer-Reviewed Original ResearchPluripotent stem cellsHuman pluripotent stem cellsHepatic organoidsStem cellsNovel platformOrganoid productionClinical translationHepatic functionalityToxicity screeningDifferentiation procedureOrganoid technologySpontaneous formationProtocolTechnologyOptimal concentrationFunctionalityPlatformIndustrial settingsOrganoidsProductionPSC
2017
Development of an inducible platform for intercellular protein delivery
Siller R, Dufour E, Lycke M, Wilmut I, Jung YW, Park IH, Sullivan GJ. Development of an inducible platform for intercellular protein delivery. International Journal Of Pharmaceutics 2017, 522: 1-10. PMID: 28254654, DOI: 10.1016/j.ijpharm.2017.02.067.Peer-Reviewed Original ResearchConceptsNovel platformBiomolecules of interestCell penetrating peptideGene of interestHuman chorionic gonadotropin beta subunitProtein deliveryStem cell biologyChorionic gonadotropin beta subunitPenetrating peptidePotential applicationsProtein transduction domainProtein of interestGreen fluorescent proteinFusion proteinGonadotropin beta subunitEfficient uptakeN-terminal signal peptideCell culture mediumPlatformFluorescent proteinTransduction domainLack of specificityBeta subunitActive proteinFixation process
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