2024
Distinct characteristics and prognosis of IgA nephropathy patients with nephrotic syndrome: a propensity score-matched cohort study
Jiang Y, Chen P, Zhao W, Liu L, Shi S, Lv J, Zhang H. Distinct characteristics and prognosis of IgA nephropathy patients with nephrotic syndrome: a propensity score-matched cohort study. Frontiers In Medicine 2024, 11: 1344219. PMID: 38439903, PMCID: PMC10910015, DOI: 10.3389/fmed.2024.1344219.Peer-Reviewed Original ResearchNephrotic syndromeEnd-stage kidney diseaseNS patientsIgAN patientsComposite endpointRisk of composite endpointElevated serum uric acid levelsSerum uric acid levelsNon-NS groupLow C3 levelsScore-matched cohort studyIgA nephropathy patientsUric acid levelsIncreased complement activationSevere foot process effacementMESTC scoreFoot process effacementPropensity score matchingRemission rateSevere hematuriaRenal biopsyActive diseaseClinical characteristicsNephropathy patientsPoor prognosis
2022
2348. Distinct cerebrospinal fluid immune proteins mark neurosyphilis
Catalano A, Yoon J, Farhadian S, Fertuzinhos S, Gisslen M, Zetterberg H, Marra C, Walsh H. 2348. Distinct cerebrospinal fluid immune proteins mark neurosyphilis. Open Forum Infectious Diseases 2022, 9: ofac492.155. DOI: 10.1093/ofid/ofac492.155.Peer-Reviewed Original ResearchHIV statusImmune responseBCA-1/CXCL13Macrophage/microglial activationIP-10/CXCL10IL-8/CXCL8CNS immune responseNeuronal injury markersNon-NS groupPotential CSF biomarkersMIG/CXCL9Date of enrollmentHigh-sensitivity ELISAWilcoxon rank sum testSpecific immune pathwaysMultiple comparisonsRank sum testRace/ethnicityCNS inflammationMicroglial activationCSF WBCElevated markersInjury markersNeuronal damageAsymptomatic disease
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