2024
Catalyst–Substrate Pairings for Carbocyclic and Heterocyclic Systems in Atroposelective Quinazolinone Synthesis
Guo M, Miller S. Catalyst–Substrate Pairings for Carbocyclic and Heterocyclic Systems in Atroposelective Quinazolinone Synthesis. ACS Catalysis 2024, 14: 17226-17232. PMID: 39912118, PMCID: PMC11793914, DOI: 10.1021/acscatal.4c05014.Peer-Reviewed Original ResearchChiral phosphoric acidPositive nonlinear effectNon-covalent interactionsQuinazolinone synthesisHeterocyclic systemsCatalyst scaffoldHigh enantioselectivityNitrogen heteroatomsEnantiomeric ratioCatalystReaction developmentCatalytic scaffoldMechanistic studiesEnantioselectivityPhosphoric acidSubstrateCarbocyclesCyclocondensationHeterocyclesHeteroatomsScaffoldsReactionSynthesisReactivityYield
2010
Structural and Functional Modifications of Corneal Crystallin ALDH3A1 by UVB Light
Estey T, Chen Y, Carpenter JF, Vasiliou V. Structural and Functional Modifications of Corneal Crystallin ALDH3A1 by UVB Light. PLOS ONE 2010, 5: e15218. PMID: 21203538, PMCID: PMC3006428, DOI: 10.1371/journal.pone.0015218.Peer-Reviewed Original ResearchConceptsActive site CysNon-native aggregationNon-covalent interactionsAldehyde dehydrogenase 3A1MALDI-TOF mass spectrometryMammalian corneal epitheliumCorneal crystallinsSpectroscopic studiesChemical modificationUV-induced damageCys residuesGlucose-6-phosphate dehydrogenaseTertiary structureMass spectrometryMultifaceted roleResult of aggregationALDH3A1Enzymatic activityCorneal proteinsUV-induced inactivationOxidative stressProteinFunctional modificationsResiduesDirect absorption
2006
Intermolecular Forces in the Self‐Assembly of Peptide Amphiphile Nanofibers
Stendahl J, Rao M, Guler M, Stupp S. Intermolecular Forces in the Self‐Assembly of Peptide Amphiphile Nanofibers. Advanced Functional Materials 2006, 16: 499-508. DOI: 10.1002/adfm.200500161.Peer-Reviewed Original ResearchPeptide amphiphile moleculesMultiple non-covalent interactionsNon-covalent interactionsCircular dichroism spectroscopyPeptide amphiphile nanofibersGel mechanical propertiesHydration of counterionsVan der WaalsThree-dimensional networkSelf-AssemblyHydrogen bondingMacroscopic gelsSupramolecular nanofibersAqueous mediaHydrophobic forcesIntermolecular forcesPA moleculesAmphiphile moleculesBulk physical propertiesIonic bridgingAmphiphile nanofibersOscillatory rheologyElectronic structureDer WaalsCounterion screening
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