2022
The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states
Mandino F, Yeow LY, Bi R, Sejin L, Bae HG, Baek SH, Lee CY, Mohammad H, Horien C, Teoh CL, Lee JH, Lai MK, Jung S, Fu Y, Olivo M, Gigg J, Grandjean J. The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states. Cerebrovascular And Brain Metabolism Reviews 2022, 42: 1616-1631. PMID: 35466772, PMCID: PMC9441719, DOI: 10.1177/0271678x221082016.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseEntorhinal cortexFunctional connectivity lossEarly AD stagesEarly Alzheimer's diseaseLateral entorhinal cortexVentral networkSynaptic hyperexcitabilityAD progressionGlobal dysfunctionMouse modelOptogenetic activationProjection targetsPathophysiological modelAD stagesMice showNetwork alterationsActive phenotypeNeuronal facilitationEarly hallmarkDiseaseActivity alterationsFMRI signalsNeuronal underpinningsTauopathies
2017
Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations
van Ede F, Niklaus M, Nobre A. Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations. Journal Of Neuroscience 2017, 37: 437-445. DOI: 10.1523/jneurosci.2272-16.2017.Peer-Reviewed Original ResearchVisual working memoryWorking memoryTemporal expectationsAttentional prioritizationNeural substratesBrain areasStudies of working memoryFlexible goal-directed behaviorMemory retrieval timeInvestigate working memoryWorking memory performanceGoal-directed behaviorEcologically valid contextInvestigated visual working memorySensory brain areasVisual brain areasMemory performanceLaboratory tasksNeuronal underpinningsMental representationsNeural mechanismsDelay intervalNeural implementationValid contextsPrecision judgments
2016
Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations
van Ede F, Niklaus M, Nobre A. Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations. Journal Of Neuroscience 2016, 37: 437-445. PMID: 28077721, PMCID: PMC5242399, DOI: 10.1523/jneurosci.2272-16.2016.Peer-Reviewed Original ResearchConceptsVisual working memoryWorking memoryTemporal expectationsAttentional prioritizationNeural substratesBrain areasStudies of working memoryFlexible goal-directed behaviorMemory retrieval timeInvestigate working memoryWorking memory performanceGoal-directed behaviorEcologically valid contextInvestigated visual working memorySensory brain areasVisual brain areasMemory performanceLaboratory tasksNeuronal underpinningsMental representationsNeural mechanismsDelay intervalNeural implementationValid contextsPrecision judgments
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