2024
Transcription factor-dependent regulatory networks of sexual reproduction in Fusarium graminearum
Kim W, Kim D, Wang Z, Liu M, Townsend J, Trail F. Transcription factor-dependent regulatory networks of sexual reproduction in Fusarium graminearum. MBio 2024, 16: e03030-24. PMID: 39589130, PMCID: PMC11708053, DOI: 10.1128/mbio.03030-24.Peer-Reviewed Original ResearchMating-type locusSexual reproductionKnockout mutantsTranscription factorsTranscriptome dataStage of sexual developmentRegulatory networksTranscriptional cascadeDevelopmental phenotypesSexual developmentAscospore productionRegulation of sexual developmentUpstream activatorSexual fruiting bodiesTranscriptional regulatory cascadeMulticellular body planRegulate sexual developmentMultiple transcription factorsFusarium graminearum</i>Systems biology approachComplex reproductive biologyEarly stages of sexual developmentArrest phenotypeTF networksFilamentous fungi
2008
C. elegans Nucleostemin Is Required for Larval Growth and Germline Stem Cell Division
Kudron MM, Reinke V. C. elegans Nucleostemin Is Required for Larval Growth and Germline Stem Cell Division. PLOS Genetics 2008, 4: e1000181. PMID: 18725931, PMCID: PMC2515194, DOI: 10.1371/journal.pgen.1000181.Peer-Reviewed Original ResearchConceptsRibosome biogenesisGermline stem cell divisionLarval arrest phenotypeGerm line functionGermline stem cellsStem cell divisionCell growthNematode C. elegansN-terminal domainStem cellsExhibit reduced levelsCell cycle arrestArrest phenotypeNucleolar factorsC. elegansRRNA transcriptionGrowth defectNucleolar functionGerm lineCell divisionLarval growthTransgenic studiesBiogenesisStable expressionProliferative state
1995
Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells
Fackler M, Krause D, Smith O, Civin C, May W. Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells. Blood 1995, 85: 3040-3047. PMID: 7538813, DOI: 10.1182/blood.v85.11.3040.bloodjournal85113040.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAntigens, CDAntigens, CD34Base SequenceCell DifferentiationGene Expression Regulation, LeukemicGrowth InhibitorsHematopoietic Stem CellsInterleukin-6Leukemia Inhibitory FactorLeukemia, MyeloidLymphokinesMacrophagesMiceMolecular Sequence DataPeptide FragmentsPhagocytosisRecombinant Fusion ProteinsTumor Cells, CulturedConceptsFull-length CD34Developmental stage-specific mannerM1 myeloid leukemia cellsTerminal myeloid differentiationMurine hematopoietic stemStage-specific mannerProgenitor cellsHematopoietic cell differentiationCD34 proteinNegative regulatory roleCytoplasmic tail domainMurine M1 myeloid leukemia cellsStem/progenitor cellsArrest phenotypeFunction of CD34Tail domainTerminal differentiationCell differentiationRegulatory roleMyeloid differentiationHematopoietic stemDomain regionLeukemia inhibitory factorHematopoietic cellsMyeloid leukemia cells
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