Assessment of auditory and vestibular damage in a mouse model after single and triple blast exposures
Mao B, Wang Y, Balasubramanian T, Urioste R, Wafa T, Fitzgerald TS, Haraczy SJ, Edwards-Hollingsworth K, Sayyid ZN, Wilder D, Sajja VSSS, Wei Y, Arun P, Gist I, Cheng AG, Long JB, Kelley MW. Assessment of auditory and vestibular damage in a mouse model after single and triple blast exposures. Hearing Research 2021, 407: 108292. PMID: 34214947, PMCID: PMC8276524, DOI: 10.1016/j.heares.2021.108292.Peer-Reviewed Original ResearchConceptsDistortion product otoacoustic emissionsAuditory brainstem responseBlast exposureInner hair cellsBlast-exposed miceOuter hair cellsHair cellsHearing lossMouse modelVestibular systemLong-term hearing lossBalance deficitsInner earBlast-induced hearing lossPeripheral vestibular systemSpiral ganglion neuronsTraumatic brain injuryProduct otoacoustic emissionsMiddle ear dysfunctionBasal cochlear turnTympanic membrane ruptureCourse of recoveryUtricular hair cellsMultiple blast exposuresVestibular damage
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