2025
Genomic landscapes of endometrioid and mucinous ovarian cancers and morphologically similar tumor types.
Hallberg D, Eastman A, Koul S, Bruhm D, Papp E, Davenport S, Adleff V, Ferreira L, Niknafs N, Medina J, Cristiano S, Hruban C, Fiksel J, Lebarbenchon K, Aparicio L, Vulpescu N, Kuo K, Ahuja N, Drapkin R, Jung E, Kim S, Eckert M, Lengyel E, Nakayama K, Ayhan A, Shih I, Wang T, Lavie O, Rennert G, Easwaran H, Baylin S, Press M, Velculescu V, Scharpf R. Genomic landscapes of endometrioid and mucinous ovarian cancers and morphologically similar tumor types. Cancer Research Communications 2025 PMID: 40981433, DOI: 10.1158/2767-9764.crc-25-0147.Peer-Reviewed Original ResearchOvarian mucinous carcinomaMucinous carcinomaGenomic landscapeGenome-wide methylation profilingEndometrioid carcinomaOvarian carcinomaOvarian cancerWhole-genome sequencingCombination of sequenceMucinous ovarian cancerMucinous ovarian carcinomaOvarian endometrioid carcinomaMorphologically similar tumorsOvarian cancer subtypesEndometrioid ovarian carcinomaUterine endometrioid carcinomaGenome sequenceGenomic analysisManagement of patientsMethylation patternsCancer Genome AtlasMethylation profilesEpigenomic alterationsCopy numberTissue of origin
2015
Genome-wide significant risk associations for mucinous ovarian carcinoma
Kelemen L, Lawrenson K, Tyrer J, Li Q, Lee J, Seo J, Phelan C, Beesley J, Chen X, Spindler T, Aben K, Anton-Culver H, Antonenkova N, Baker H, Bandera E, Bean Y, Beckmann M, Bisogna M, Bjorge L, Bogdanova N, Brinton L, Brooks-Wilson A, Bruinsma F, Butzow R, Campbell I, Carty K, Chang-Claude J, Chen Y, Chen Z, Cook L, Cramer D, Cunningham J, Cybulski C, Dansonka-Mieszkowska A, Dennis J, Dicks E, Doherty J, Dörk T, du Bois A, Dürst M, Eccles D, Easton D, Edwards R, Eilber U, Ekici A, Engelholm S, Fasching P, Fridley B, Gao Y, Gentry-Maharaj A, Giles G, Glasspool R, Goode E, Goodman M, Grownwald J, Harrington P, Harter P, Hasmad H, Hein A, Heitz F, Hildebrandt M, Hillemanns P, Hogdall E, Hogdall C, Hosono S, Iversen E, Jakubowska A, Jensen A, Ji B, Karlan B, Kellar M, Kelley J, Kiemeney L, Krakstad C, Kjaer S, Kupryjanczyk J, Lambrechts D, Lambrechts S, Le N, Lee A, Lele S, Leminen A, Lester J, Levine D, Liang D, Lissowska J, Lu K, Lubinski J, Lundvall L, Massuger L, Matsuo K, McGuire V, McLaughlin J, McNeish I, Menon U, Modugno F, Moes-Sosnowska J, Moysich K, Narod S, Nedergaard L, Ness R, Nevanlinna H, Adenan N, Odunsi K, Olson S, Orlow I, Orsulic S, Weber R, Paul J, Pearce C, Pejovic T, Pelttari L, Permuth-Wey J, Pike M, Poole E, Ramus S, Risch H, Rosen B, Rossing M, Rothstein J, Rudolph A, Runnebaum I, Rzepecka I, Salvesen H, Schildkraut J, Schwaab I, Shu X, Shvetsov Y, Siddiqui N, Sieh W, Song H, Southey M, Sucheston L, Tangen I, Teo S, Terry K, Thompson P, Tworoger S, van Altena A, Van Nieuwenhuysen E, Vergote I, Vierkant R, Wang-Gohrke S, Walsh C, Wentzensen N, Whittemore A, Wicklund K, Wilkens L, Sawicki W, Woo Y, Wu X, Wu A, Yang H, Zheng W, Ziogas A, Sellers T, Freedman M, Chenevix-Trench G, Pharoah P, Gayther S, Berchuck A. Genome-wide significant risk associations for mucinous ovarian carcinoma. Nature Genetics 2015, 47: 888-897. PMID: 26075790, PMCID: PMC4520768, DOI: 10.1038/ng.3336.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinoma, MucinousBase SequenceCell Line, TumorCell NucleusChromosomes, Human, Pair 2FemaleGene Expression Regulation, NeoplasticGenetic Association StudiesGenetic Predisposition to DiseaseGenome-Wide Association StudyGreen Fluorescent ProteinsHomeodomain ProteinsHumansMicroscopy, FluorescenceMolecular Sequence DataNeoplasm ProteinsOvarian NeoplasmsPolymorphism, Single NucleotideQuantitative Trait LociReverse Transcriptase Polymerase Chain ReactionRisk Factors
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