1993
Effects of Ioversol versus Iothalamate on Endothelin Release and Radiocontrast Nephropathy
HEYMAN S, CLARK B, CANTLEY L, SPOKES K, ROSEN S, BREZIS M, EPSTEIN F. Effects of Ioversol versus Iothalamate on Endothelin Release and Radiocontrast Nephropathy. Investigative Radiology 1993, 28: 313-318. PMID: 8478171, DOI: 10.1097/00004424-199304000-00011.Peer-Reviewed Original ResearchConceptsEffects of ioversolEndothelin releaseRadiocontrast nephropathyRadiocontrast agentsEqui-iodine dosesRelease of endothelinLow-osmolar agentsCultured bovine aortic endothelial cellsAortic endothelial cellsRenal vasoconstrictionBovine aortic endothelial cellsRenal vasoconstrictorCreatinine clearanceRenal functionOsmolar agentsRenal toxicityMorphologic damageNormal ratsVascular endotheliumSalt depletionNephropathyRenal medullaRatsEndothelial cellsIoversol
1982
Kinetics, competition, and selectivity of tubular absorption of proteins
Sumpio BE, Maack T. Kinetics, competition, and selectivity of tubular absorption of proteins. American Journal Of Physiology 1982, 243: f379-f392. PMID: 7124951, DOI: 10.1152/ajprenal.1982.243.4.f379.Peer-Reviewed Original ResearchConceptsBeta 2MTubular absorptionHuman growth hormoneLow perfusate calcium concentrationsPerfusate calcium concentrationMorphologic damageTubular epitheliumProximal tubulesGrowth hormoneRat kidneyCationic proteinCalcium concentrationSaturable processSaturating loadSelective effectLuminal wallLow apparent affinityTubulesImportant determinantReversible mannerApparent affinityMicrovilliProteinKidney
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