Comparison of hepatocellular carcinoma in American and Asian patients by tissue array analysis
Song T, Fong Y, Cho S, Gönen M, Hezel M, Tuorto S, Choi S, Kim Y, Suh S, Koo B, Chae Y, Jarnagin W, Klimstra D. Comparison of hepatocellular carcinoma in American and Asian patients by tissue array analysis. Journal Of Surgical Oncology 2012, 106: 84-88. PMID: 22234941, PMCID: PMC3346847, DOI: 10.1002/jso.23036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAsian PeopleBiomarkers, TumorCarcinoma, HepatocellularCyclin D1Cyclin-Dependent Kinase Inhibitor p21FemaleGene Expression Regulation, NeoplasticHepatitis BHepatitis CHumansImmunohistochemistryKi-67 AntigenLiver NeoplasmsLymphatic MetastasisMaleMiddle AgedNeoplasm InvasivenessParaffinPrognosisProliferating Cell Nuclear AntigenProto-Oncogene Proteins c-bcl-2Proto-Oncogene Proteins c-mdm2Republic of KoreaRisk FactorsTissue Array AnalysisTumor Suppressor Protein p53United StatesConceptsHepatocellular carcinomaKorea University Medical CenterMolecular pathogenesis of hepatocellular carcinomaMolecular targeted therapyViral hepatitis infectionWestern hepatocellular carcinomaMarkers of proliferationTissue array analysisPathogenesis of hepatocellular carcinomaComparisons of hepatocellular carcinomaExpression of Ki67Expression of p53University Medical CenterMDM2 stainingMicroarray sectionsNo significant differenceAsian patientsTissue microarrayVascular invasionHepatitis infectionImmunohistochemical stainingPositive stainingRegulation of cell cycleHCC specimensPathologic correlation
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