2006
The calcium-sensitive large-conductance potassium channel (BK/MAXI K) is present in the inner mitochondrial membrane of rat brain
Douglas R, Lai J, Bian S, Cummins L, Moczydlowski E, Haddad G. The calcium-sensitive large-conductance potassium channel (BK/MAXI K) is present in the inner mitochondrial membrane of rat brain. Neuroscience 2006, 139: 1249-1261. PMID: 16567053, DOI: 10.1016/j.neuroscience.2006.01.061.Peer-Reviewed Original ResearchConceptsLarge conductance voltageInner mitochondrial membraneCalcium-sensitive channelsCytochrome c oxidaseMitochondrial membraneInner mitochondrial membrane proteinC oxidaseMitochondrial fractionInner membrane 23Mitochondrial-specific proteinsMitochondrial membrane proteinMicrotubule-associated protein 1Endoplasmic reticulum markerImmuno-gold electron microscopyLarge-conductance potassium channelsDiscrete subcellular fractionsGold particle labellingWestern blottingGolgi proteinsMembrane proteinsSubcellular localizationAlpha subunitProtein 1Mitochondrial pelletMitochondria
1988
Mitochondrial Import and Processing of Mutant Human Ornithine Transcarbamylase Precursors in Cultured Cells
Isaya G, Fenton W, Hendrick J, Furtak K, Kalousek F, Rosenberg L. Mitochondrial Import and Processing of Mutant Human Ornithine Transcarbamylase Precursors in Cultured Cells. Molecular And Cellular Biology 1988, 8: 5150-5158. DOI: 10.1128/mcb.8.12.5150-5158.1988.Peer-Reviewed Original ResearchLeader peptideMitochondrial importMutant precursorHeLa cellsAssociated with mitochondriaHuman ornithine transcarbamylaseAmino acid substitutionsOrnithine transcarbamylase precursorIntact HeLa cellsIntramitochondrial locationLack of bindingMutant proteinsMitochondrial matrixAcid substitutionsActive enzymeActive trimerMitochondrial fractionTrypsin protectionAffinity columnFractionation studiesMitochondriaCultured cellsCytosolOrnithine transcarbamylaseMutations
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