2009
Understanding Modularity in Molecular Networks Requires Dynamics
Alexander RP, Kim PM, Emonet T, Gerstein MB. Understanding Modularity in Molecular Networks Requires Dynamics. Science Signaling 2009, 2: pe44. PMID: 19638611, PMCID: PMC4243459, DOI: 10.1126/scisignal.281pe44.Peer-Reviewed Original ResearchConceptsMolecular networksBiological networksMolecular network analysisAnalysis of modularityCellular machinesMolecular partsSystems biologyFunctional analysisGenome sequencingCellular behaviorCollective functionsMolecular interactionsSmall moleculesNetwork analysisRecent advancesIntense researchBiologyFundamental goalSequencingMajor advancesMoleculesInteractionIsolationModularity
2007
The road to modularity
Wagner GP, Pavlicev M, Cheverud JM. The road to modularity. Nature Reviews Genetics 2007, 8: 921-931. PMID: 18007649, DOI: 10.1038/nrg2267.Peer-Reviewed Original ResearchConceptsProtein-protein interaction networkMolecular systems biologyPatterns of evolutionGene duplicationGene regulationEvolutionary biologyNeutral mutationsBiological organizationQuantitative traitsInteraction networksSystems biologyStructure of macromoleculesEnvironmental conditionsBiologyDuplicationTraitsMutationsRegulationSelectionModularityMacromolecules
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