Immunohistochemical detection of ARID1A in colorectal carcinoma: loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage
Ye J, Zhou Y, Weiser M, Gönen M, Zhang L, Samdani T, Bacares R, DeLair D, Ivelja S, Vakiani E, Klimstra D, Soslow R, Shia J. Immunohistochemical detection of ARID1A in colorectal carcinoma: loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage. Human Pathology 2014, 45: 2430-2436. PMID: 25311944, DOI: 10.1016/j.humpath.2014.08.007.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdolescentAdultAgedAged, 80 and overCarcinoma, MedullaryColorectal NeoplasmsDNA MethylationDNA Mismatch RepairDNA-Binding ProteinsFemaleHumansImmunohistochemistryMaleMicrosatellite InstabilityMiddle AgedMutL Protein Homolog 1Neoplasm StagingNuclear ProteinsPilot ProjectsPromoter Regions, GeneticTranscription FactorsYoung AdultConceptsMicrosatellite unstable colorectal carcinomasLynch syndrome screeningMMR-deficient casesMedullary histologyMismatch repairMMR-deficient tumorsColorectal carcinomaDNA mismatch repairSyndrome screeningOlder agePilot studyAssociationARID1A lossOvarian cancerLoss of stainingIncreased rateConsecutive seriesMicrosatellite unstable tumorsChromatin remodeling genesMLH1Lynch
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply