2011
Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis
Sumigray KD, Chen H, Lechler T. Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis. Journal Of Cell Biology 2011, 194: 631-642. PMID: 21844209, PMCID: PMC3160577, DOI: 10.1083/jcb.201104009.Peer-Reviewed Original ResearchMeSH Keywords1-Alkyl-2-acetylglycerophosphocholine Esterasealpha CateninAnimalsCarrier ProteinsCell DifferentiationCell ProliferationCells, CulturedDesmoplakinsDesmosomesEpidermisFluorescent Antibody TechniqueKeratinocytesMiceMice, KnockoutMicrotubule-Associated ProteinsMicrotubulesPermeabilityProtein TransportRecombinant Fusion ProteinsTransfectionConceptsDesmosomal protein desmoplakinCortical microtubule organizationCentrosomal proteinsMicrotubule organizationCell cortexMicrotubule reorganizationCell-cell adhesion structuresPenetrant perinatal lethalityDramatic defectsDesmosome stabilityCytoskeletal networkAdhesion structuresPerinatal lethalityUnexpected roleSingle isoformDesmosomal componentsBarrier activityCell typesDesmosomal proteinsEpidermal differentiationKeratin filamentsIntermediate filamentsProteinLIS1Specific subset
1992
Erks: their fifteen minutes has arrived.
Crews CM, Alessandrini A, Erikson RL. Erks: their fifteen minutes has arrived. Molecular Cancer Research 1992, 3: 135-42. PMID: 1504018.Peer-Reviewed Original ResearchConceptsProtein kinaseCell cycleYeast cellsTyrosine kinase signalsERK protein kinasesSea star oocytesSpecific transcriptional factorsAmino acid residuesSpecific differentiation eventsG0-G1 transitionExtracellular signalsKinase signalsPhosphorylation signalsSignal transductionTranscriptional changesS6 kinaseRaf-1Differentiation eventsMitogenic signalsYeast enzymeGene productsMicrotubule reorganizationDownstream targetsTranscriptional factorsEGF receptor
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