Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial
Jimenez J, Munroe E, Weirauch A, Fiorino K, Culter C, Nelson K, Labaki W, Choi P, Co I, Standiford T, Prescott H, Hyzy R. Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial. Critical Care 2023, 27: 21. PMID: 36650593, PMCID: PMC9843117, DOI: 10.1186/s13054-023-04315-x.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureAcute respiratory distress syndromeRespiratory distress syndromeDistress syndromeRandomized crossover pilot trialCrossover pilot trialModerate-severe acute respiratory distress syndromePEEP titrationStatic respiratory system complianceMethodsA single-centerPositive end-expiratory pressure titrationRespiratory system compliancePilot trialPositive end-expiratory pressure selectionEnd-expiratory pressureConclusionsIn patientsEIT-guided PEEP titrationPaO2/FiO2 ratioBackgroundIn patientsSingle-centerMechanical ventilationStatistically significant changesPrimary outcomeSecondary outcomesDriving pressure
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