Learning-augmented sketching offers improved performance for privacy preserving and secure GWAS
Xu J, Zhu K, Cai J, Kockan C, Dokmai N, Cho H, Woodruff D, Sahinalp S. Learning-augmented sketching offers improved performance for privacy preserving and secure GWAS. IScience 2025, 28: 112011. PMID: 40124506, PMCID: PMC11927738, DOI: 10.1016/j.isci.2025.112011.Peer-Reviewed Original ResearchTrusted Execution EnvironmentGenome-wide association studiesPublic training datasetsComputational resource constraintsOptimize memory usageIntel SGXPrivacy guaranteesPrivacy preservationExecution environmentCloud providersMemory usageMemory constraintsTraining datasetDatasetResource constraintsHigher accuracyPrivacyDedicated memoryExperimental resultsImproved performanceSignificant SNPsGWA studiesAssociation studiesGenotype dataSNPs
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