2023
Apolipoprotein E polymorphism‐dependent effects on cellular function
Beyer B, Levine Z. Apolipoprotein E polymorphism‐dependent effects on cellular function. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.077424.Peer-Reviewed Original ResearchApolipoprotein EStructure:function relationshipsCombination of cell-basedIsogenic hiPSC linesTransport of lipidsSubcellular localizationE4 isoformCellular functionsFunction of apolipoprotein EBiophysical approachesLiving cellsTransport of E2Cell typesCo-localizationCentral nervous systemLipoprotein particlesIsoformsHuman astrocytesRelationship of apolipoprotein EHiPSC linesCell-basedInvestigate mechanismsApolipoproteinCellsOrganelles
2018
Dissociable effects of the apolipoprotein-E (APOE) gene on short- and long-term memories
Zokaei N, Čepukaitytė G, Board A, Mackay C, Husain M, Nobre A. Dissociable effects of the apolipoprotein-E (APOE) gene on short- and long-term memories. Neurobiology Of Aging 2018, 73: 115-122. PMID: 30342272, PMCID: PMC6261846, DOI: 10.1016/j.neurobiolaging.2018.09.017.Peer-Reviewed Original ResearchConceptsLong-term memoryFunction of apolipoproteinsLong-term memory impairmentLong-term memory performanceMeasures of reportingPreclinical Alzheimer's diseasePhenotypic effectsMemory advantageNeural underpinningsItem identityMemory impairmentMemory performanceMeasure memoryShort-term memoryAlzheimer's diseaseDissociative effectsE4 alleleEffect of genotypeE4 carriersAllelesMemoryObject locationGenotypesApolipoproteinShort-
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