Mechanical Properties of Doubly Stabilized Microtubule Filaments
Hawkins T, Sept D, Mogessie B, Straube A, Ross J. Mechanical Properties of Doubly Stabilized Microtubule Filaments. Biophysical Journal 2013, 104: 1517-1528. PMID: 23561528, PMCID: PMC3617445, DOI: 10.1016/j.bpj.2013.02.026.Peer-Reviewed Original ResearchConceptsMicrotubule-stabilizing factorsChemotherapeutic drug taxolMicrotubule-associated proteinsRigidity of microtubulesPresence of taxolProperties of microtubulesNucleotide stateGuanosine-5'-O-(3-thiotriphosphateMechanical properties of microtubulesCytoskeletal filamentsDrug taxolMicrotubulesIntracellular organismsTubulin dimersTreated cellsCell typesCell morphologyMicrotubule mechanicsTaxolAnticancer agentsCellsGuanosine-5NucleotideBinding of drugsMAP4
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