Reversible induction of translational isoforms of p53 in glucose deprivation
Khan D, Katoch A, Das A, Sharathchandra A, Lal R, Roy P, Das S, Chattopadhyay S, Das S. Reversible induction of translational isoforms of p53 in glucose deprivation. Cell Death & Differentiation 2015, 22: 1203-1218. PMID: 25721046, PMCID: PMC4572868, DOI: 10.1038/cdd.2014.220.Peer-Reviewed Original ResearchConceptsIRES activityP53 isoformsMaster transcription regulatorTumor suppressor protein p53Bicistronic reporter constructCritical tumor suppressorSuppressor protein p53Glucose deprivationFull-length p53P53 IRES activityP53 mRNACell cycle arrestTranscription regulatorsNutrient starvationTranslational regulationEndoplasmic reticulum stressDifferent stress conditionsNuclear proteinsInternal ribosome entry site (IRES) structureGlucose starvationTarget genesCellular pathwaysStarvation-induced increaseReporter constructsTumor suppressor
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply