2017
Neuropilins in Lymphatic Development and Function
Han J, Zarkada G, Eichmann A. Neuropilins in Lymphatic Development and Function. 2017, 109-124. DOI: 10.1007/978-3-319-48824-0_7.Peer-Reviewed Original Research
2013
A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development
Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND. A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development 2013, 140: 1497-1506. PMID: 23462469, PMCID: PMC3596992, DOI: 10.1242/dev.084152.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAnimalsAnimals, Genetically ModifiedAutocrine CommunicationBlood VesselsCell MovementCodon, NonsenseEmbryo, NonmammalianFemaleLymphatic SystemMiceMice, KnockoutNeovascularization, PhysiologicParacrine CommunicationProtein IsoformsSignal TransductionVascular Endothelial Growth Factor CZebrafishZebrafish ProteinsConceptsMigratory persistenceLymphatic developmentSensitized genetic backgroundTip cell positionVascular endothelial growth factor CEndothelial cell dynamicsDeficient endothelial cellsFactor CTime-lapse analysisMutant embryosVertebrate embryosTruncation alleleEctopic blood vesselsFilopodia stabilityAngiogenesis defectsDistinct modesEndothelial cellsDevelopmental angiogenesisLymphatic vasculatureVascular developmentLymphatic defectsGenetic backgroundReceptor FLT4VEGFCCell position
2012
Lymphatics thrive on stress: mechanical force in lymphatic development
Schwartz MA, Simons M. Lymphatics thrive on stress: mechanical force in lymphatic development. The EMBO Journal 2012, 31: 781-782. PMID: 22334045, PMCID: PMC3280563, DOI: 10.1038/emboj.2011.484.Peer-Reviewed Original ResearchConceptsLymphatic developmentBlood vessel developmentLymphatic vasculatureVessel developmentMechanical forces
2009
FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1
Norrmén C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Ylä-Herttuala S, Alitalo K, Petrova TV. FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. Journal Of Cell Biology 2009, 185: 439-457. PMID: 19398761, PMCID: PMC2700385, DOI: 10.1083/jcb.200901104.Peer-Reviewed Original ResearchConceptsLymphatic vessel maturationGenome-wide mapsVessel maturationLymphatic endothelial cellsTranscription factor NFATc1Blood vessel maturationLymphatic developmentNovel regulatorLymphatic maturationUnsuspected linkFOXC2Control formationLymphatic collecting vesselsBlood vasculatureNFATc1Potential targetMaturationIntense investigationEndothelial cellsLymphatic vesselsLymphatic dysfunctionMorphological characterizationRegulatorEnhancerTherapeutic interventions
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply