2018
Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1.
DeLong JH, Hall AO, Konradt C, Coppock GM, Park J, Harms Pritchard G, Hunter CA. Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1. The Journal Of Immunology 2018, 200: 1761-1770. PMID: 29358280, PMCID: PMC5821564, DOI: 10.4049/jimmunol.1701154.Peer-Reviewed Original ResearchConceptsT cell expressionIL-27T cellsEffector cellsSca-1Cell expressionPathogen-specific T cellsMemory precursor effector cellsEndogenous IL-27Identification of CD8Type I IFNMemory stem cellsCytokine-mediated signalsEffector CD4Ly6C expressionSca-1 expressionImmune populationsT-betExpression of Ly6CMemory populationMouse CD4I IFNLy6CIFNMouse splenocytes
2011
Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection
Marshall HD, Chandele A, Jung YW, Meng H, Poholek AC, Parish IA, Rutishauser R, Cui W, Kleinstein SH, Craft J, Kaech SM. Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection. Immunity 2011, 35: 633-646. PMID: 22018471, PMCID: PMC3444169, DOI: 10.1016/j.immuni.2011.08.016.Peer-Reviewed Original ResearchConceptsAcute viral infectionViral infectionEffector cellsTfh cell markersVirus-specific effectorT helper 1Th1 effector cellsT-bet expressionIL-7R expressionMemory precursor cellsTh1 CD4Helper 1Memory TTh1 cellsProliferative responseSecondary infectionEffector typeReliable markerCell markersInfectionPrecursor cellsGene expression profilesLy6CCell featuresCell development
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