Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi: A genomic and spatial analysis
Chitwood M, Corbett E, Ndhlovu V, Sobkowiak B, Colijn C, Andrews J, Burke R, Cudahy P, Dodd P, Imai-Eaton J, Engelthaler D, Folkerts M, Feasey H, Lan Y, Lewis J, McNichol J, Menzies N, Chipungu G, Nliwasa M, Weinberger D, Warren J, Salomon J, MacPherson P, Cohen T. Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi: A genomic and spatial analysis. PLOS Global Public Health 2025, 5: e0004040. PMID: 40173177, PMCID: PMC11964229, DOI: 10.1371/journal.pgph.0004040.Peer-Reviewed Original ResearchHigh HIV prevalence citiesTime of tuberculosisPoor health outcomesCity-wide interventionsTransmission of M. tuberculosisHealth outcomesTargeted interventionsHighest tuberculosis burdenTargeted screeningGeneral populationGeographic concentrationSurveillance dataCommunity characteristicsTuberculosis burdenLocal tacticsBlantyreWhole-genome sequencingInfectious tuberculosisCulture-positive tuberculosis casesInterventionMalawiSustained impactTreated individualsCityEvidence of local transmission
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