Neurogenetics of Dynamic Connectivity Patterns Associated With Obsessive-Compulsive Symptoms in Healthy Children
Suñol M, Alemany S, Bustamante M, Diez I, Contreras-Rodríguez O, Laudo B, Macià D, Martínez-Vilavella G, Martínez-Zalacaín I, Menchón J, Pujol J, Sunyer J, Sepulcre J, Soriano-Mas C. Neurogenetics of Dynamic Connectivity Patterns Associated With Obsessive-Compulsive Symptoms in Healthy Children. Biological Psychiatry Global Open Science 2021, 2: 411-420. PMID: 36324658, PMCID: PMC9616269, DOI: 10.1016/j.bpsgos.2021.11.009.Peer-Reviewed Original ResearchObsessive-compulsive symptomsDynamic functional connectivityObsessive-compulsive disorderBrain circuitsGlutamatergic neurotransmissionBrain regionsNeurobiological models of obsessive-compulsive disorderModels of obsessive-compulsive disorderObsessive Compulsive Inventory-Child VersionResting-state functional magnetic resonance imaging examinationObsessive–compulsive disorder samplesPatterns of dynamic functional connectivityRight superior parietal cortexAssociated with connectivity changesDynamic functional connectivity changesInvolvement of glutamatergic neurotransmissionLeft ventral putamenFunctional magnetic resonance imaging examinationSuperior parietal cortexStable connectivity patternsBrain network changesGraph theory-based approachNeurobiological modelsVentral putamenSymptom levels
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