2025
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy
Guo M, Wu Y, Hobson C, Su Y, Qian S, Krueger E, Christensen R, Kroeschell G, Bui J, Chaw M, Zhang L, Liu J, Hou X, Han X, Lu Z, Ma X, Zhovmer A, Combs C, Moyle M, Yemini E, Liu H, Liu Z, Benedetto A, La Riviere P, Colón-Ramos D, Shroff H. Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy. Nature Communications 2025, 16: 313. PMID: 39747824, PMCID: PMC11697233, DOI: 10.1038/s41467-024-55267-x.Peer-Reviewed Original ResearchConceptsAdaptive optics techniquesMulti-photonDeep learning-based strategyAberration compensationLearning-based strategyTrained neural networkImprove image qualityOptical aberrationsNeural networkImage quantitationOptical techniquesDiverse datasetsSuper-resolution microscopyLight sheetRestore dataImage qualityImage signalNetworkImage inspectionImage acquisitionImage stacksOpticsResolutionImagesFluorescence microscopy
2024
Developing deep learning-based strategies to predict the risk of hepatocellular carcinoma among patients with nonalcoholic fatty liver disease from electronic health records
Li Z, Lan L, Zhou Y, Li R, Chavin K, Xu H, Li L, Shih D, Zheng W. Developing deep learning-based strategies to predict the risk of hepatocellular carcinoma among patients with nonalcoholic fatty liver disease from electronic health records. Journal Of Biomedical Informatics 2024, 152: 104626. PMID: 38521180, DOI: 10.1016/j.jbi.2024.104626.Peer-Reviewed Original ResearchDeep learning modelsElectronic health recordsHCC risk predictionHealth recordsTime-varying covariatesLearning modelsElectronic health record dataRisk predictionHealth record dataAccuracy of deep learning modelsDeep learning-based strategyCovariate imbalanceDisease prediction tasksLearning-based strategyDeep learning performanceDisease risk predictionEHR databaseClassification problemLength of follow-upTransfer learningFatty liver diseasePrediction taskCarcinoma riskModel trainingRecord data
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