2024
Psilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats
Floris G, Dabrowski K, Zanda M, Daws S. Psilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats. Molecular Psychiatry 2024, 30: 1801-1816. PMID: 39433903, PMCID: PMC12015112, DOI: 10.1038/s41380-024-02788-y.Peer-Reviewed Original ResearchPrefrontal cortexHeroin seekingHeroin relapseDrug seekingSelf-AdministrationPrefrontal cortex of male ratsPrefrontal cortex of animalsCortex of male ratsHeroin self-administrationHeroin-seeking behaviorDrug-naive ratsOpioid-seeking behaviorSerotonin 2A receptorEfficacy of psilocybinAlcohol seekingHeroin takingForced abstinenceNucleus accumbensRelapse testRelapse behaviorIL-17AMaladaptive behaviorsPsychedelic compoundsAntagonist ketanserinPsilocybin
2003
In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors
Hajós M, Gartside S, Varga V, Sharp T. In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors. Neuropharmacology 2003, 45: 72-81. PMID: 12814660, DOI: 10.1016/s0028-3908(03)00139-4.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexMPFC neuronesWAY-100635Systemic administrationPrefrontal cortexAntagonist WAY 100635Midbrain raphe nucleiMedian raphe nucleusRat ventromedial prefrontal cortexMRN stimulationVentral medial prefrontal cortexPost-stimulus inhibitionAntagonist ketanserinRaphe nucleusAntidromic spikesIontophoretic applicationNAD-299Neuronal activityProjection neuronesElectrical stimulationVentromedial prefrontal cortexVentral partVivo inhibitionNeuronesElectrophysiological responses
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply