2025
Ionophore-Based Molecular Layer-by-Layer Polyamide Membranes for Facilitated Single-Ion Transport
Zhang J, Villalobos L, Lee J, Zhong M, Elimelech M. Ionophore-Based Molecular Layer-by-Layer Polyamide Membranes for Facilitated Single-Ion Transport. ACS Applied Materials & Interfaces 2025, 17: 30817-30824. PMID: 40359549, DOI: 10.1021/acsami.5c02331.Peer-Reviewed Original ResearchIon-selective polymeric membraneMolecular layer-by-layerEfficient ion separationIon binding featuresPolyamide membranesHigher binding energyBiological ion channelsLayer-by-layerIon separationPolyamide filmsPolymeric membranesIon selectivityBinding energySingle-ionIon bindingBinding featuresBinary salt mixturesIon transportCationsNernst-Planck equationCompetitive bindingSalt mixtureSub-10Nernst-PlanckIon fluxA molecular systems perspective on calcium oscillations beyond ion fluxes
Xiong D, Tong C, Wu M. A molecular systems perspective on calcium oscillations beyond ion fluxes. Current Opinion In Cell Biology 2025, 94: 102523. PMID: 40311263, PMCID: PMC12113571, DOI: 10.1016/j.ceb.2025.102523.Peer-Reviewed Original Research
2022
FliL ring enhances the function of periplasmic flagella
Guo S, Xu H, Chang Y, Motaleb MA, Liu J. FliL ring enhances the function of periplasmic flagella. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2117245119. PMID: 35254893, PMCID: PMC8931381, DOI: 10.1073/pnas.2117245119.Peer-Reviewed Original ResearchConceptsFlagellar motorBacterial motilityCryo-electron tomographyStator complexFlagellar proteinsMutant cellsPeriplasmic flagellaActive conformationSitu structureFascinating questionsSupramolecular complexesMotilityComplexesMotBOptimal functionFliLFlagellaIon fluxProteinFunctionAssemblyRemodelingCellsConformationBorrelia
2004
WNK kinases: molecular regulators of integrated epithelial ion transport
Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP. WNK kinases: molecular regulators of integrated epithelial ion transport. Current Opinion In Nephrology & Hypertension 2004, 13: 557-562. PMID: 15300163, DOI: 10.1097/00041552-200409000-00012.Peer-Reviewed Original ResearchConceptsPseudohypoaldosteronism type IIWNK kinasesPotassium ion channelsChloride ion fluxIon channelsSerine-threonine kinaseCoordinated regulationDiverse epitheliaMolecular regulatorsMolecular switchKinasePotassium ion secretionDynamic regulatorGeneral roleDisease physiologyIon fluxIntegrated regulationElectrolyte homeostasisEpithelial ion transportEpithelial transportersEssential roleWNK4HomeostasisFlux pathwaysMutations
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