2024
Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias
Ouyang Y, Li F, Li X, Bynum J, Mor V, Taljaard M. Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias. Trials 2024, 25: 732. PMID: 39478608, PMCID: PMC11523597, DOI: 10.1186/s13063-024-08404-2.Peer-Reviewed Original ResearchConceptsIntra-cluster correlation coefficientIntra-cluster correlation coefficient estimationSample size calculationED visitsMedicare dataMedicare fee-for-service beneficiariesEmergency departmentFee-for-service beneficiariesSize calculationDiagnosis of ADRDNational Medicare dataCluster randomized trialHospital referral regionsHospital service areasHealth care systemBackgroundCluster randomized trialsPopulation-level dataRandomized trialsDesign of cluster randomized trialsEvaluate interventionsReferral regionsCare systemICC estimatesADRDCorrelation coefficient
2018
A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes
Zhou X, Liao X, Kunz LM, Normand ST, Wang M, Spiegelman D. A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes. Biostatistics 2018, 21: 102-121. PMID: 30084949, PMCID: PMC7410259, DOI: 10.1093/biostatistics/kxy031.Peer-Reviewed Original ResearchConceptsVariable cluster sizesMaximum likelihood approachLikelihood approachCluster sizeLeast squares approachStatistical theoryCluster random effectsBinary outcomesNumber of clustersNumerical methodParameter spaceRobustness of powerAsymptotic powerSquares approachIntra-cluster correlation coefficientRandom effectsParallel clusterLarge-scale intervention programmesPower calculationNew methodAvailable methodsWedge designSequential rolloutTheoryClusters
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