Recent advances of sterile inflammation and inter-organ cross-talk in alcoholic liver disease
Shim Y, Jeong W. Recent advances of sterile inflammation and inter-organ cross-talk in alcoholic liver disease. Experimental & Molecular Medicine 2020, 52: 772-780. PMID: 32457490, PMCID: PMC7272465, DOI: 10.1038/s12276-020-0438-5.Peer-Reviewed Original ResearchConceptsDamage-associated molecular patternsAlcoholic liver diseaseNon-parenchymal cellsSterile inflammationLiver diseaseGeneration of damage-associated molecular patternsCellular pattern recognition receptorsMultiple pro-inflammatory cytokinesSpectrum of alcoholic liver diseaseToll-like receptorsPro-inflammatory cytokinesHepatic stellate cellsAlcoholic liver injuryPattern recognition receptorsDouble-stranded RNACross-talkInter-organ cross-talkAlcohol-mediatedBone marrowImmune cellsInduce de novo lipogenesisMitochondrial double-stranded RNALiver injuryKupffer cellsPortal circulation
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