2024
Phenotypic Heterogeneity in Pathogens
Sherry J, Rego E. Phenotypic Heterogeneity in Pathogens. Annual Review Of Genetics 2024, 58: 183-209. PMID: 39083846, DOI: 10.1146/annurev-genet-111523-102459.Peer-Reviewed Original ResearchPhenotypic heterogeneityGenetically identical populationSalmonella typhimurium</i>Genetic diversityPathogen diversityPathogen populationsBacterial pathogensPathogen subpopulationsGenetic heterogeneityInvading pathogensHost organismFluctuating environmentsInfectious disease progressionPathogensIdentical populationsTreatment escapeInfection outcomesHeterogeneous subpopulationsDisease progressionInfecting organismDiversityCausative linkGeneticsSubpopulationsPhenotype
1989
Ceftriaxone Compared with Cefotaxime for Serious Bacterial Infections
Smith C, Petty B, Hendrix C, Kernan W, Garver P, Fox K, Beamer A, Carbone K, Threlkeld M, Lietman P. Ceftriaxone Compared with Cefotaxime for Serious Bacterial Infections. The Journal Of Infectious Diseases 1989, 160: 442-447. PMID: 2668428, DOI: 10.1093/infdis/160.3.442.Peer-Reviewed Original ResearchConceptsSerious bacterial infectionsBacterial infectionsDouble-blind clinical trialSuspected serious bacterial infectionResponse rateCefotaxime 2 gCeftriaxone 2 gDose of ceftriaxoneTreatment groupsDose of cefotaximeFrequency of diarrheaClinical responseAnaerobic infectionsProthrombin timeCeftriaxoneClinical trialsCefotaximeInfecting organismInfectionAdverse effectsDoseTreatmentDaysThrombophlebitisProthrombin
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