2022
Functionalized DNA-Origami-Protein Nanopores Generate Large Transmembrane Channels with Programmable Size-Selectivity
Shen Q, Xiong Q, Zhou K, Feng Q, Liu L, Tian T, Wu C, Xiong Y, Melia T, Lusk C, Lin C. Functionalized DNA-Origami-Protein Nanopores Generate Large Transmembrane Channels with Programmable Size-Selectivity. Journal Of The American Chemical Society 2022, 145: 1292-1300. PMID: 36577119, PMCID: PMC9852090, DOI: 10.1021/jacs.2c11226.Peer-Reviewed Original ResearchConceptsExchange of macromoleculesCholesterol-rich membranesHybrid nanoporesSynthetic biologyBiophysical toolsSynthetic cellsTransmembrane channelsTransmembrane nanoporesDNA ringsProtein nanoporeCell membraneBacterial toxinsDNA origami techniqueLipid membranesAnalytical chemistryMacromolecule sizeDNA origamiMembraneProgrammable sizeNanoporesSized poresNucleoporinsAverage inner diameterCellsPneumolysin
2020
Dried blood spots for the identification of bioaccumulating organic compounds: Current challenges and future perspectives
Jobst KJ, Arora A, Pollitt KG, Sled JG. Dried blood spots for the identification of bioaccumulating organic compounds: Current challenges and future perspectives. Current Opinion In Environmental Science & Health 2020, 15: 66-73. PMID: 33073071, PMCID: PMC7560987, DOI: 10.1016/j.coesh.2020.07.001.Peer-Reviewed Original ResearchOrganic compoundsTrace level contaminantsAnalytical chemistryArt mass spectrometryMass spectrometryField of exposomicsChemical pollutantsMost environmental exposuresCompoundsCurrent challengesConstituent compoundsFuture perspectivesChemistryDBS analysisSpectrometryPollutantsExogenous chemicalsContaminantsChemicalsDry blood spotsExposomicsMixtureExposomeReliable approach
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