2005
Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice
Ohmura K, Johnsen A, Ortiz-Lopez A, Desany P, Roy M, Besse W, Rogus J, Bogue M, Puech A, Lathrop M, Mathis D, Benoist C. Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 12489-12494. PMID: 16113081, PMCID: PMC1194932, DOI: 10.1073/pnas.0504325102.Peer-Reviewed Original ResearchConceptsInbred strainsWhole-genome scanQuantitation of transcriptsInterleukin-1 gene familyConventional inbred strainsWild-derived strainsComplex genetic controlSequence haplotypesGenomic regionsGenetic lociNoncoding polymorphismsCandidate genesGenetic analysisGenetic differencesBALB/c haplotypeGenetic controlGene expressionIL-1B gene expressionBreeding strategiesBreeding schemesIL1B geneGenesSerum-transfer arthritisStrainHigh-responder BALB/c
1985
Xenopus MHC class II molecules. II. Polymorphism as determined by two-dimensional gel electrophoresis.
Kaufman J, Flajnik M, Du Pasquier L. Xenopus MHC class II molecules. II. Polymorphism as determined by two-dimensional gel electrophoresis. The Journal Of Immunology 1985, 134: 3258-64. PMID: 3980992, DOI: 10.4049/jimmunol.134.5.3258.Peer-Reviewed Original ResearchConceptsTwo-dimensional gel electrophoresisGel electrophoresisRemoval of N-linked glycansXenopus laevisN-terminal sequenceN-linked glycansBiosynthetically labeled cellsClass II antigensPolymorphic classIEF procedureGlycosylated materialAlpha chainPHA-stimulated blood cellsBeta chainInbred strainsEndo FII antigensElectrophoresisMHC typeLaevisOutbred animalsCellsHaplotypesGlycansClones
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