Asymmetric synthesis of amines using tert-butanesulfinamide
Xu HC, Chowdhury S, Ellman JA. Asymmetric synthesis of amines using tert-butanesulfinamide. Nature Protocols 2013, 8: 2271-2280. PMID: 24157547, DOI: 10.1038/nprot.2013.134.Peer-Reviewed Original ResearchConceptsTert-butanesulfinamideAsymmetric synthesisClick chemistry applicationsReliable asymmetric synthesisDiversity-oriented synthesisChemistry applicationsCarbonyl compoundsNucleophile additionAmine reagentsPeptide isosteresChiral aminesDifferent amine structuresAmine structureClasses of aminesGroup cleavageBioactive moleculesAminesDrug candidatesSynthesisTertiary carbinaminesBiological purposesPharmaceutical agentsPreparationDifferent biological purposesIsosteres
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