2009
A critical review of human endotoxin administration as an experimental paradigm of depression
DellaGioia N, Hannestad J. A critical review of human endotoxin administration as an experimental paradigm of depression. Neuroscience & Biobehavioral Reviews 2009, 34: 130-143. PMID: 19666048, PMCID: PMC2795398, DOI: 10.1016/j.neubiorev.2009.07.014.Peer-Reviewed Original ResearchConceptsImmune system activationEndotoxin administrationSystem activationImmune stimuliDepressive symptomsInnate immune system activationElicit depressive symptomsInterferon-alpha treatmentCommon final pathwayPotential molecular pathwaysImmunologic abnormalitiesImmune depressionVaccine administrationInflammatory cytokinesDepression paradigmDepressed patientsFinal pathwaySymptomsDepression researchAdministrationDepressionMolecular pathwaysBehavioral changesActivationRodents
2001
Viral latency--the papillomavirus model.
Broker TR, Jin G, Croom-Rivers A, Bragg SM, Richardson M, Chow LT, Vermund SH, Alvarez RD, Pappas PG, Squires KE, Hoesley CJ. Viral latency--the papillomavirus model. 2001, 106: 443-51; discussion 452-3, 465-75. PMID: 11761260.Peer-Reviewed Original ResearchConceptsHPV typesHPV DNAAIDS cohortEnd-stage renal failureCervico-vaginal lavageKidney transplantation candidatesConsequence of immunosuppressionHuman papillomavirus infectionLower genital tractDifferent HPV typesLatent viral infectionFunctional immune systemHIV/AIDSSub-clinical stateHPV prevalenceHIV cohortHPV infectionKidney transplantationNested polymerase chain reaction amplificationPapillomavirus infectionRenal failureTransplantation candidatesHPV 6Immune depressionImmunosuppressive conditions
1987
Thymic hypoplasia, splenomegaly and immune depression in guinea pigs with neonatal cytomegalovirus infection
Zheng Z, Lavallee J, Bia F, Griffith B. Thymic hypoplasia, splenomegaly and immune depression in guinea pigs with neonatal cytomegalovirus infection. Developmental & Comparative Immunology 1987, 11: 407-418. PMID: 3040485, DOI: 10.1016/0145-305x(87)90084-x.Peer-Reviewed Original ResearchConceptsGuinea pigsCMV infectionCytomegalovirus infectionThymic hypoplasiaProliferative responseImmune proliferative responsesNeonatal cytomegalovirus infectionAcute CMV infectionT lymphocyte populationsNeonatal guinea pigsT cell mitogensConcanavalin AB cell mitogensImmunodepressive effectImmune depressionLymphocyte populationsSpleen cellsInfectious virusGrowth retardationDissimilar alterationsHigh titersSpleenInfectionThymusSplenomegaly
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