An AUDacious Proposal: How to Improve Gastroenterology Fellow Training for Alcohol Use Disorder and Alcohol-Associated Liver Disease
Ilagan-Ying Y. An AUDacious Proposal: How to Improve Gastroenterology Fellow Training for Alcohol Use Disorder and Alcohol-Associated Liver Disease. Digestive Diseases And Sciences 2025, 1-4. PMID: 40512451, DOI: 10.1007/s10620-025-09144-2.Peer-Reviewed Original ResearchAlcohol-associated liver diseaseAlcohol use disorderGastroenterology fellowsOne-hour educational interventionHealth professional traineesMultidisciplinary care modelAttitudes of providersAttitudes of cliniciansLife-saving careAddiction medicine specialistsManagement of alcohol use disorderALD-related mortalityUse disorderAlcohol use disorder pharmacotherapiesTertiary academic care centerVulnerable patient populationPrimary careCare modelHealth professionalsEducational interventionMedicine providersAddiction providersProfessional traineesLiver diseaseTreatment gapPreliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial
O’Malley S, Miranda R, Book S, Chun T, Liss T, Malcolm R, Muvvala S, Padovano H, Schacht J, Blackburn B, Diamond I, Ransom J, Ryan M, Falk D, Litten R. Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial. Alcohol And Alcoholism 2025, 60: agaf001. PMID: 39829301, PMCID: PMC11744046, DOI: 10.1093/alcalc/agaf001.Peer-Reviewed Original ResearchAlcohol use disorderAldehyde dehydrogenase 2 inhibitorUse disorderTreat alcohol use disorderCue reactivity sessionsCue-elicited cravingCue-induced cravingHuman laboratory studiesTreatment-seeking adultsAlcohol use disorder pharmacotherapiesAldehyde dehydrogenase 2Multisite clinical trialDose to placeboWeeks of medicationEffect size estimatesReactivation sessionDrinking outcomesGroup differencesCravingMeasured 1 weekEffect sizeCohen's dDouble-blindPreliminary effectivenessAlcohol consumption
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