2021
Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline
Ferkowicz M, Winfree S, Sabo A, Kamocka M, Khochare S, Barwinska D, Eadon M, Cheng Y, Phillips C, Sutton T, Kelly K, Dagher P, El-Achkar T, Dunn K, Project F, Knight R, Lecker S, Stillman I, Mcmahon G, Waikar S, Weins A, Hacohen N, Hoover P, Aulisio M, Cooperman L, Herlitz L, O'toole J, Poggio E, Sedor J, Appelbaum P, Barasch J, Bomback A, D'agati V, Kiryluk K, Mehl K, Shang N, Weng C, Barisoni L, Alexandrov T, Ashkar T, Barwinska D, Dagher P, Dunn K, Eadon M, Ferkowicz M, Kelly K, Sutton T, Winfree S, Menez S, Parikh C, Rosenberg A, Villalobos P, Slack A, Rosas S, Williams M, Azeloglu E, He C, Iyengar R, Parikh S, Anderton C, Pasa-Tolic L, Velickovic D, Oliver G, Ardayfio J, Bebiak J, Brown K, Campbell T, Campbell C, Hayashi L, Jefferson N, Koewler R, Roberts G, Saul J, Shpigel A, Stutzke E, Wright L, Miegs L, Pinkeney R, Sealfon R, Troyanskaya O, Tuttle K, Goltsev Y, Lake B, Zhang K, Dobi D, Joanes M, Laszik Z, Nolan G, Schroeder A, Balis U, He O, Hodgin J, Kretzler M, Mariani L, Menon R, Otto E, Schaub J, Steck B, Elder M, Hall D, Kellum J, Kruth M, Murugan R, Palevsky P, Randhawa P, Rosengart M, Sims-Lucas S, Stefanick M, Stull S, Tublin M, Alpers C, De Boer I, Fullerton M, Himmelfarb J, Mcclelland R, Mooney S, Shankland S, Williams K, Blank K, Dighe A, Carson J, Dowd F, Drager Z, Sharma K, Zhang G, Kermani A, Lee S, Lu C, Miller T, Moe O, Park H, Sambandam K, Sanchez F, Torrealba J, Robert T, Vazquez M, Wang N, Gaut J, Jain S, Vijayan A, Luciano R, Moledina D, Ugochukwu U, Wilson F. Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Laboratory Investigation 2021, 101: 661-676. PMID: 33408350, PMCID: PMC8363780, DOI: 10.1038/s41374-020-00518-w.Peer-Reviewed Original ResearchConceptsSingle-cell techniquesCell physiologyTissue cytometryClinical tissue samplesHuman kidney tissueTissue samplesPersonalized medicineMolecular informationQuantitative censusAdvent of personalized medicineSpectral confocal microscopyRenal biopsyConfocal microscopyDiabetic nephropathyPathology of kidney diseaseKidney diseaseFlow cytometryIntact tissueCellsHuman nephrectomyHuman kidneyCytometryVolumetric Tissue Exploration
2017
A Survey of Patient Attitudes Toward Participation in Biopsy-Based Kidney Research
Moledina DG, Cheung B, Kukova L, Luciano RL, Peixoto AJ, Wilson FP, Alfano S, Parikh CR. A Survey of Patient Attitudes Toward Participation in Biopsy-Based Kidney Research. Kidney International Reports 2017, 3: 412-416. PMID: 29725645, PMCID: PMC5932306, DOI: 10.1016/j.ekir.2017.11.008.Peer-Reviewed Original ResearchAdditional needle passesKidney tissueKidney biopsyKidney diseasePatients' attitudesNeedle passesHealth/National InstituteMultivariable logistic modelNational InstituteNovel therapeutic targetHuman kidney tissueBiopsy complicationsAfrican American participantsLower oddsBiopsyTherapeutic targetPrecision Medicine InitiativePatientsMedicine InitiativeTissueDiseaseKidney researchParticipantsAdditional burdenTotal
2014
Quantification and localization of M2 macrophages in human kidneys with acute tubular injury
Palmer MB, Vichot AA, Cantley LG, Moeckel GW. Quantification and localization of M2 macrophages in human kidneys with acute tubular injury. International Journal Of Nephrology And Renovascular Disease 2014, 7: 415-419. PMID: 25404860, PMCID: PMC4230184, DOI: 10.2147/ijnrd.s66936.Peer-Reviewed Original ResearchAcute tubular injuryMinimal change diseaseM2 macrophagesTubular epithelial cellsTubular injuryMacrophage populationsEpithelial cellsBiopsy-proven diagnosisUltra-structural examinationProximal tubule cellsTubular basement membraneBasement membraneHuman kidney sectionsHuman kidney tissueHLA-DRChange diseaseAbove diagnosisInterstitial macrophagesM1 macrophagesM2 phenotypeInterstitial macrophage populationKidney sectionsKidney tissuePatientsTubule cells
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