2024
Metabolic Determinants of Ferroptosis in B-Cell Lymphoma
Leveille E, Bramson E, Robinson M, Bertomeu T, Chatr-Aryamontri A, Kothari S, Müschen M. Metabolic Determinants of Ferroptosis in B-Cell Lymphoma. Blood 2024, 144: 976-976. DOI: 10.1182/blood-2024-209077.Peer-Reviewed Original ResearchB-cell lymphomaB-cell malignanciesB cellsSensitivity to ferroptosisLipid membrane remodelingFerroptosis inducersMyeloid leukemiaSolid tumorsMembrane remodelingCRISPR screensGene dependenciesAssociated with significantly worse survivalTreatment of B-cell lymphomaB-cell lymphoma modelElimination of B cellsPUFA metabolismCysteine-glutamate antiporterCell deathMature splenic B cellsTherapy-resistant tumorsNon-apoptotic form of cell deathAnalysis of clinical dataDominant-negative p53Vulnerability to ferroptosisWhole-genome CRISPR screen
2023
P-238 Non-interventional study comparing the effectiveness and safety of r-hFSH:r-hLH versus r-hFSH in women aged 35-42 years with normal ovarian reserve undergoing GnRH antagonist ART treatment
Arvis P, Lehert P, Chuderland D, Schwarze J, Helwig C, Bidet M, Guivarc'h Leveque A, Lispi M, D'Hooghe T. P-238 Non-interventional study comparing the effectiveness and safety of r-hFSH:r-hLH versus r-hFSH in women aged 35-42 years with normal ovarian reserve undergoing GnRH antagonist ART treatment. Human Reproduction 2023, 38 DOI: 10.1093/humrep/dead093.596.Peer-Reviewed Original ResearchNormal ovarian reserveR-hLHR-hFSHLive birth rateOvarian stimulationOvarian reserveNon-interventional studyART treatmentFrench centersLive birthsPregnancy rateOS cyclesClinical pregnancy rateAdvanced maternal ageOngoing pregnancy rateOvarian reserve biomarkersLow ovarian reserveAnalysis of clinical dataSubgroup of patientsFollow-up periodPregnancy failure rateBirth rateSecondary analysis of clinical dataClinical pregnancyAMH levels
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