2024
Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site
Ihedioha O, Marcarian H, Sivakoses A, Beverley S, McMahon-Pratt D, Bothwell A. Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site. Frontiers In Immunology 2024, 15: 1473133. PMID: 39502693, PMCID: PMC11534728, DOI: 10.3389/fimmu.2024.1473133.Peer-Reviewed Original ResearchParasite-infected miceBALB/c miceDickkopf-1Infection siteInfected BALB/c micePathogen-associated molecular patternsWild-type BALB/c miceLevels of apoptosisNull mutantsLeishmania infectionDickkopf-1 levelsDraining Lymph NodesNeutrophil-platelet aggregatesLeukocyte-platelet aggregatesInfiltration of neutrophilsReduced neutrophil activationDay 3 PIResponse to infectionSignaling pathwayHost-related factorsMolecular patternsMembrane componentsLRP6Lymph nodesTh2 differentiation
2023
Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface
Correa-Martinez C, Leopold S, Köck R, Kossow A, Bauwens A, Mellmann A. Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface. 2023, 355-372. DOI: 10.1007/978-3-031-27164-9_9.Peer-Reviewed Original ResearchHemolytic uremic syndromeShiga toxin-producing E. coliEnterohemorrhagic E. coliContamination of meatContamination of plantsFarm environmentToxin-producing E. coliAnimal reservoirsNon-O157 strainsHost-related factorsSevere intestinal diseaseFood chainPathogenic subgroupSignificant clinical concernMajor reservoirBovine fecesTransmission routesUremic syndromeEHEC serotype O157Intestinal diseaseHerdsEnterohemorrhagic Escherichia coliImplementation of measuresOutbreak identificationClinical concern
2022
Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface
Correa-Martinez C, Leopold S, Köck R, Kossow A, Bauwens A, Mellmann A. Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface. 2022, 1-19. DOI: 10.1007/978-3-030-85877-3_9-1.Peer-Reviewed Original ResearchHemolytic uremic syndromeShiga toxin-producing E. coliEnterohemorrhagic E. coliContamination of meatContamination of plantsFarm environmentToxin-producing E. coliAnimal reservoirsNon-O157 strainsHost-related factorsSevere intestinal diseaseFood chainPathogenic subgroupSignificant clinical concernMajor reservoirBovine fecesTransmission routesUremic syndromeEHEC serotype O157Intestinal diseaseHerdsEnterohemorrhagic Escherichia coliImplementation of measuresOutbreak identificationClinical concern
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