2022
Outcomes Stratification of Head and Neck Cancer Using Pre- and Post-treatment DNA Methylation From Peripheral Blood
Qian D, Ulrich B, Peng G, Zhao H, Conneely K, Miller A, Bruner D, Eldridge R, Wommack E, Higgins K, Shin D, Saba N, Smith A, Burtness B, Park H, Stokes W, Beitler J, Xiao C. Outcomes Stratification of Head and Neck Cancer Using Pre- and Post-treatment DNA Methylation From Peripheral Blood. International Journal Of Radiation Oncology • Biology • Physics 2022, 115: 1217-1228. PMID: 36410685, DOI: 10.1016/j.ijrobp.2022.11.009.Peer-Reviewed Original ResearchConceptsRecurrence-free survivalWorse recurrence-free survivalOverall survivalMethylation risk scoreRadiation therapyValidation cohortPeripheral bloodDiscovery cohortOutcome stratificationShorter recurrence-free survivalNeck squamous cell carcinomaGastrostomy tube insertionHigher neutrophil countOral cavity cancerAforementioned risk factorsSquamous cell carcinomaPeripheral blood samplesNonmetastatic HNSCCNeutrophil countPrognostic factorsCox regressionPrognostic valueCell carcinomaTube insertionImmune modulation
2021
204 The role of neutrophils in the clinical severity of lupus nephritis patients with concurrent skin disease
Osmani L, Pettus J, Roy A, Skopelja-Gardner S. 204 The role of neutrophils in the clinical severity of lupus nephritis patients with concurrent skin disease. Lupus Science & Medicine 2021, 8: a5-a5. DOI: 10.1136/lupus-2021-lupus21century.8.Peer-Reviewed Original ResearchConcurrent skin diseasesHigher neutrophil countLupus nephritisSkin rashLN flareSkin diseasesSkin inflammationHigh neutrophilLN patientsLupus patientsNeutrophil countLupus nephritis biopsiesNeutrophil-lymphocyte ratioWorse kidney functionOnly female patientsRole of neutrophilsAnti-dsDNA IgGActivation of neutrophilsT-testStudent's t-testRenal inflammatoryActive diseaseKidney injuryChart reviewIgA depositionOutcomes Stratification of Head and Neck Cancer Using Pre- and Post-Treatment DNA Methylation in Peripheral Blood
Qian D, Ulrich B, Peng G, Zhao H, Conneely K, Miller A, Bruner D, Eldridge R, Wommack E, Higgins K, Shin D, Saba N, Smith A, Burtness B, Park H, Stokes W, Beitler J, Xiao C. Outcomes Stratification of Head and Neck Cancer Using Pre- and Post-Treatment DNA Methylation in Peripheral Blood. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: s143-s144. DOI: 10.1016/j.ijrobp.2021.07.323.Peer-Reviewed Original ResearchProgression-free survivalSquamous cell carcinomaOverall survivalHigh-risk scoreRisk scoreDiscovery cohortValidation cohortPeripheral bloodRisk factorsNon-metastatic squamous cell carcinomaMethods Peripheral blood samplesWorse progression-free survivalShorter progression-free survivalPoor progression-free survivalNeck squamous cell carcinomaHPV-negative statusPEG tube insertionPost-treatment time pointsCompletion of radiotherapyHigher neutrophil countOral cavity cancerNeck cancer recurrenceAforementioned risk factorsPeripheral blood samplesClinicopathologic covariates
2011
Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization
Rocha L, Seixas M, Cerqueira B, Lopes V, Reis M, Goncalves M. Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization. Blood 2011, 118: 2140. DOI: 10.1182/blood.v118.21.2140.2140.Peer-Reviewed Original ResearchHigh ferritin serum levelsFerritin serum levelsSCD patientsSerum levelsS. pneumoniaeNasopharyngeal colonizationNasopharynx colonizationHbSS genotypeSickle cell disease childrenS. aureusBacteria colonizationBiomarkers of hemolysisHigher leukocyte numbersPneumococcal penicillin resistanceHigher neutrophil countS. pneumoniae colonizationCause of infectionCross-sectional studyOccurrence of infectionMultivariate analysis modelNeutrophil countSCD childrenHigh ferritinPneumonia occurrencePneumoniae colonization
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