Impact of Obesity and Body Fat Distribution on Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma
Gaujoux S, Torres J, Olson S, Winston C, Gonen M, Brennan M, Klimstra D, D’Angelica M, DeMatteo R, Fong Y, House M, Jarnagin W, Kurtz R, Allen P. Impact of Obesity and Body Fat Distribution on Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma. Annals Of Surgical Oncology 2012, 19: 2908-2916. PMID: 22411205, DOI: 10.1245/s10434-012-2301-y.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedBlood Loss, SurgicalBody Fat DistributionBody Mass IndexDisease-Free SurvivalFemaleHumansIntra-Abdominal FatKaplan-Meier EstimateMaleMiddle AgedObesityOperative TimePancreatic NeoplasmsPancreaticoduodenectomyProportional Hazards ModelsStatistics, NonparametricSurvival RateConceptsVisceral fat areaBody fat distributionBody mass indexBody mass index classTumor characteristicsFat distributionCancer-related outcomesPancreatic adenocarcinomaPathological characteristicsClinical relevance of obesityVisceral fat area quartilesVisceral fat area valuesSignificantly higher blood lossInfluence of body mass indexDisease-free survivalPancreatic cancer riskPancreatic fatty infiltrationRelevance of obesityHigher blood lossInfluence of obesityImpact of obesityPancreatic ductal adenocarcinomaResultsA significant positive correlationIncreased body weightBlood loss
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