2017
Primary melanoma histologic subtype (HS) impacts melanoma specific survival (MSS) and response to systemic therapy.
Lattanzi M, Lee Y, Robinson E, Weiss S, Moran U, Simpson D, Shapiro R, Berman R, Pavlick A, Wilson M, Kirchhoff T, Zhong J, Osman I. Primary melanoma histologic subtype (HS) impacts melanoma specific survival (MSS) and response to systemic therapy. Journal Of Clinical Oncology 2017, 35: 9577-9577. DOI: 10.1200/jco.2017.35.15_suppl.9577.Peer-Reviewed Original ResearchMelanoma-specific survivalWorse melanoma-specific survivalHistologic subtypeNodular melanomaNYU cohortSEER cohortMetastatic settingSystemic therapyPrimary histologic subtypeCheckpoint inhibitor immunotherapyMultivariate Cox modelThick primary tumorsDifferent clinical behaviorPrimary nodular melanomaNext-generation sequencingSignificant predictorsClinical Trial ReportingLow mutational burdenMutational landscapeHigh mitotic indexSpecific survivalWorse prognosisClinical behaviorPrimary tumorMelanoma survival
2006
Outcome Following Surgical Therapy for Gastrointestinal Stromal Tumors
Gupta M, Sheppard B, Corless C, MacDonell K, Blanke C, Billingsley K. Outcome Following Surgical Therapy for Gastrointestinal Stromal Tumors. Journal Of Gastrointestinal Surgery 2006, 10: 1099-1105. PMID: 16966028, DOI: 10.1016/j.gassur.2006.05.014.Peer-Reviewed Original ResearchConceptsGastrointestinal stromal tumorsMultivisceral resectionStromal tumorsMetastatic diseaseSurgical resectionImatinib mesylateDuodenal gastrointestinal stromal tumorKIT-positive gastrointestinal stromal tumoursCox proportional hazards modelPercent of patientsComplete surgical resectionKaplan-Meier methodLog-rank analysisPresence of metastasesLimits of resectionProportional hazards modelMitotic indexHigh mitotic indexActuarial survivalPostoperative survivalIncomplete resectionSurgical therapyComplete resectionImproved survivalIndependent predictors
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply