215-OR: Increased White Adipose Tissue Oxidative Capacity and Insulin Resistance Are Early Changes upon High-Fat Diet in Healthy Humans
XOURAFA G, GRANATA C, TRENKAMP S, KORZEKWA B, SCHRAUWEN-HINDERLING V, PETERSEN K, SHULMAN G, KAHL S, RODEN M. 215-OR: Increased White Adipose Tissue Oxidative Capacity and Insulin Resistance Are Early Changes upon High-Fat Diet in Healthy Humans. Diabetes 2025, 74 DOI: 10.2337/db25-215-or.Peer-Reviewed Original ResearchWhite adipose tissueFat mass indexInsulin resistanceHigh-fat dietLipid contentEuropean Association for the StudyNon-esterified fatty acidsInsulin sensitivityLiver lipid contentParallel-group studyEuropean Association for the Study of DiabetesNon-obese individualsAdipose tissue insulin resistanceWhole-body insulin sensitivityPromote insulin resistanceTissue insulin resistanceHepatic ATP levelsHigh-resolution respirometryHyperinsulinemic-euglycemic clampMitochondrial respirationStudy of DiabetesWhole-body insulin resistanceInsulin stimulationHepatic lipid contentHypercaloric high-fat diet
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply