Preclinical study of patient-specific cell-free nanofiber tissue-engineered vascular grafts using 3-dimensional printing in a sheep model
Fukunishi T, Best CA, Sugiura T, Opfermann J, Ong CS, Shinoka T, Breuer CK, Krieger A, Johnson J, Hibino N. Preclinical study of patient-specific cell-free nanofiber tissue-engineered vascular grafts using 3-dimensional printing in a sheep model. Journal Of Thoracic And Cardiovascular Surgery 2016, 153: 924-932. PMID: 27938900, PMCID: PMC5715716, DOI: 10.1016/j.jtcvs.2016.10.066.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationComputed Tomography AngiographyComputer-Aided DesignEndothelial CellsExtracellular MatrixMacrophagesModels, AnimalMyocytes, Smooth MuscleNanostructuresNanotechnologyNeointimaPhlebographyPrinting, Three-DimensionalProsthesis DesignSheep, DomesticTime FactorsTissue EngineeringVascular PatencyVascular RemodelingVena Cava, InferiorVenous PressureConceptsTissue-engineered vascular graftsSimilar mechanical propertiesComplex anatomical shapesMechanical propertiesVascular graftsNative inferior vena cavaBiodegradable scaffoldsComputer-aided designFeasible technologyNanofiber scaffoldsBiomechanical evaluationPrintingPressure gradientMandrelWall thicknessScaffoldsTechnologyAnatomic requirementsThicknessLayerDepositionEndothelialization
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