2013
The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil
Xu J, Xu P, Li Z, Xiao L, Yang Z. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cellular & Molecular Biology Letters 2013, 18: 494-506. PMID: 23990403, PMCID: PMC6275801, DOI: 10.2478/s11658-013-0102-3.Peer-Reviewed Original ResearchConceptsGlycogen synthase kinase-3βSynthase kinase-3βGSK-3β activationC6 cell apoptosisCell apoptosisHoechst 33342 stainingGSK-3βKinase-3βSelective small molecule inhibitorsSmall molecule inhibitorsGlioma cell apoptosisFlow cytometryCell deathReceptor signalingMolecule inhibitorsTime-dependent mannerNMDA receptor signalingTumor cell apoptosisTumor cell proliferationCellular levelCell proliferationApoptosisC6 cell deathN-methyl-D-aspartate receptorsCell viability
2011
GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions
Li Q, Michaud M, Canosa S, Kuo A, Madri JA. GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions. Angiogenesis 2011, 14: 173-185. PMID: 21253820, DOI: 10.1007/s10456-011-9201-9.Peer-Reviewed Original ResearchMeSH KeywordsAminophenolsAnimalsBasic Helix-Loop-Helix Transcription Factorsbeta CateninBrainCell CommunicationCell DifferentiationCell MovementCell ProliferationEndothelial CellsEnzyme ActivationGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaHypoxia-Inducible Factor 1, alpha SubunitIntercellular Signaling Peptides and ProteinsMaleMaleimidesMiceMice, Inbred C57BLNeovascularization, PhysiologicNeural Stem CellsNeurogenesisPhosphorylationPhosphoserineReceptor Cross-TalkSignal TransductionSolubilitySpecies SpecificityConceptsNeural stem cellsNotch-1 expressionHIF-1αGSK-3βSDF-1III-tubulinStem cellsPremature infant populationMicrovascular endothelial cellsGSK-3β activationCD1 levelsEndothelial cell interactionsNeurogenic areasVascular proliferationInfant populationGSK-3β inhibitorTherapeutic potentialSVZ tissueGreater angiogenesisHIF-2αMouse strainsΒ-catenin participatesEndothelial cellsReciprocal modulation
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