Associations among rearing environment and the infant gut microbiome with early-life neurodevelopment and cognitive development in a nonhuman primate model (Macaca mulatta)
Daiy K, Wiley K, Allen J, Bailey M, Dettmer A. Associations among rearing environment and the infant gut microbiome with early-life neurodevelopment and cognitive development in a nonhuman primate model (Macaca mulatta). Journal Of Developmental Origins Of Health And Disease 2025, 16: e1. PMID: 39781670, PMCID: PMC11731890, DOI: 10.1017/s2040174424000400.Peer-Reviewed Original ResearchConceptsMother-peer-rearedNursery-rearedEmotional responsesInfant gut microbiomeCognitive developmentGut microbiomeNonhuman primate modelInfant emotional responsivenessLow emotional responsivenessInfant rhesus monkeysNeonatal neurobehavioral assessmentGut microbiome alpha diversityReward associationsCognitive flexibilityPattern of microbial compositionGut microbiome developmentPrimate modelCognitive functionImpact brainDifferential abundance analysisMicrobiome alpha diversityBehavioral developmentMotor maturityVisual orientationFactor analysis
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