2007
Transgenic RNAi Depletion of Claudin-16 and the Renal Handling of Magnesium*
Hou J, Shan Q, Wang T, Gomes A, Yan Q, Paul D, Bleich M, Goodenough D. Transgenic RNAi Depletion of Claudin-16 and the Renal Handling of Magnesium*. Journal Of Biological Chemistry 2007, 282: 17114-17122. PMID: 17442678, DOI: 10.1074/jbc.m700632200.Peer-Reviewed Original ResearchConceptsClaudin-16Tight junction proteinsTight junction proteins claudin-16Junction proteinsRenal handlingTight junctionsRenal handling of magnesiumRenal wasting of magnesiumParacellular ion reabsorptionHandling of magnesiumKnock-downFamilial hypomagnesemiaRenal functionElectrolyte disordersCation channelsTarget of drug developmentAscending limbMouse modelFHHNCParacellular cation channelsControl of ion homeostasisRenal controlIn vivo analysisIon reabsorptionNephrocalcinosis
1981
Adverse effects of liquid protein fast on the handling of magnesium, calcium and phosphorus
Licata A, Lantigua R, Amatruda J, Lockwood D. Adverse effects of liquid protein fast on the handling of magnesium, calcium and phosphorus. The American Journal Of Medicine 1981, 71: 767-772. PMID: 7304647, DOI: 10.1016/0002-9343(81)90362-4.Peer-Reviewed Original ResearchConceptsUrinary lossMagnesium levelsUrinary titratable acid excretionFecal lossSerum bicarbonate levelsSerum calcium levelsTitratable acid excretionMeq of potassiumNegative mineral balanceSkeletal storesMetabolic wardUrinary calciumObese subjectsSerum phosphorusRenal lossUrinary ammoniumDietary intakeHandling of magnesiumExcretion of phosphorusMineral metabolismSerum valuesAcid excretionBicarbonate levelsCalcium levelsLiquid protein
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