Insulin resistance and glucose transporter expression during the euglycemic hyperinsulinemic clamp in the lamb
Gelardi N, Rapoza R, Renzulli J, Cowett R. Insulin resistance and glucose transporter expression during the euglycemic hyperinsulinemic clamp in the lamb. American Journal Of Physiology 1999, 277: e1142-e1149. PMID: 10600805, DOI: 10.1152/ajpendo.1999.277.6.e1142.Peer-Reviewed Original ResearchConceptsEuglycemic hyperinsulinemic clampHyperinsulinemic clampAge-matched lambsYoung animalsEndogenous glucose productionInsulin-resistant statesGLUT-4 protein expressionEffect of insulinGLUT-2 expressionGLUT-4 expressionGlucose transporter expressionInsulin resistanceGreater glucose utilizationAcute changesMU xGlucose utilizationGlucose productionYounger groupOlder groupTransporter expressionOld animalsProtein expressionInsulinPercent decrease
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