Tumoral Intraductal Neoplasms of the Bile Ducts Comprise Morphologically and Genetically Distinct Entities.
Wang T, Askan G, Ozcan K, Rana S, Zehir A, Bhanot U, Yantiss R, Rao D, Wahl S, Bagci P, Balci S, Balachandran V, Jarnagin W, Adsay N, Klimstra D, Basturk O. Tumoral Intraductal Neoplasms of the Bile Ducts Comprise Morphologically and Genetically Distinct Entities. Archives Of Pathology & Laboratory Medicine 2023, 147: 1390-1401. PMID: 36821179, DOI: 10.5858/arpa.2022-0343-oa.Peer-Reviewed Original ResearchConceptsIntraductal oncocytic papillary neoplasmIntraductal papillary neoplasmIntraductal tubulopapillary neoplasmIntraductal neoplasmsPapillary neoplasmBile ductTargeted Next-Generation SequencingMale to female ratioHigh-grade dysplasiaRecurrent genetic aberrationsCopy number variantsTumor suppressor geneFollow-up informationDisease-related deathNext-generation sequencingWnt Signaling PathwayGenetically distinct entitiesCK20 expressionGenetic aberrationsFemale ratioFollow-upTubulopapillary neoplasmNeoplasmsSuppressor geneFrequent alterations
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