2016
Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage–Induced Senescence Program in Gastric Cancer
Francica P, Nisa L, Aebersold D, Langer R, Bladt F, Blaukat A, Stroka D, Martínez M, Zimmer Y, Medová M. Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage–Induced Senescence Program in Gastric Cancer. Clinical Cancer Research 2016, 22: 5322-5336. PMID: 27185371, DOI: 10.1158/1078-0432.ccr-15-2987.Peer-Reviewed Original ResearchConceptsDNA damage-induced senescenceMET inhibitionMET targetingGastric tumorsNegative regulator of senescenceHuman gastric cancer cell linesGastric cancer cell linesInfliction of DNA damageAberrant MET expressionEctopic expression of FoxM1Tumor tissue microarraysCopy number alterationsRegulation of senescenceMET receptor tyrosine kinaseDepletion of FOXM1Receptor tyrosine kinasesGastric tumor cellsExpression of FoxM1Cancer cell linesCancer Genome AtlasDownregulation of FoxM1Deregulated signalingDownstream effectorsNegative regulatorTumor radiosensitivityEndoscopic submucosal dissection of gastric tumors: A systematic review and meta-analysis
Akintoye E, Obaitan I, Muthusamy A, Akanbi O, Olusunmade M, Levine D. Endoscopic submucosal dissection of gastric tumors: A systematic review and meta-analysis. World Journal Of Gastrointestinal Endoscopy 2016, 8: 517-532. PMID: 27606044, PMCID: PMC4980641, DOI: 10.4253/wjge.v8.i15.517.Peer-Reviewed Original ResearchGastric endoscopic submucosal dissectionEndoscopic submucosal dissectionR0 resectionResection rateSubmucosal dissectionGastric tumorsCurative resection rateFirst-line therapyR0 resection rateComprehensive literature searchMajor bleedingLine therapyResection statusClinical efficacyRecurrence rateSafety profileTumor recurrencePerforation rateStudy heterogeneitySystematic reviewMedical literatureLiterature searchTumorsWarrants considerationResection
2001
Family history of cancer and risk of esophageal and gastric cancers in the United States
Dhillon P, Farrow D, Vaughan T, Chow W, Risch H, Gammon M, Mayne S, Stanford J, Schoenberg J, Ahsan H, Dubrow R, West A, Rotterdam H, Blot W, Fraumeni J. Family history of cancer and risk of esophageal and gastric cancers in the United States. International Journal Of Cancer 2001, 93: 148-152. PMID: 11391635, DOI: 10.1002/ijc.1294.Peer-Reviewed Original ResearchConceptsNon-cardia gastric adenocarcinomaFamily historyGastric cancerEsophageal cancerGastric adenocarcinomaEsophageal adenocarcinomaEsophageal squamous cell cancerNon-cardia gastric cancerEsophageal squamous cell carcinomaSquamous cell cancerRisk of esophagealSquamous cell carcinomaCase-control studyGastric cardia adenocarcinomaHigh incidence areaGastric cardiaIncreased riskCell carcinomaDigestive cancersRisk factorsStomach cancerProstate cancerBreast cancerGastric tumorsCardia adenocarcinoma
1999
Endo-organ and laparoscopic management of gastric leiomyomas.
Seelig M, Hinder R, Floch N, Klingler P, Seelig S, Branton S, Woodward T. Endo-organ and laparoscopic management of gastric leiomyomas. Surgical Laparoscopy Endoscopy & Percutaneous Techniques 1999, 9: 78-81. PMID: 9950137, DOI: 10.1097/00019509-199901000-00019.Peer-Reviewed Original ResearchConceptsSubmucosal tumorGastric leiomyomaGastric lesionsPosterior wall of the stomachSubmucosal gastric tumorWall of the stomachBenign gastric lesionsPosterior gastric wallTreatment of lesionsTreatment of gastric lesionsLaparoscopic managementLaparoscopic treatmentLaparoscopic techniqueEsophagogastric junctionGastric surgeryGastric tumorsPosterior wallEndoscopic guidanceAnterior wallTumorLaparoscopic gastrotomyLesionsGastric wallLeiomyomaTreatment
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