Chapter 31. Solid-Phase Synthesis: Applications to Combinatorial Libraries
Choong I, Ellman J. Chapter 31. Solid-Phase Synthesis: Applications to Combinatorial Libraries. Annual Reports In Medicinal Chemistry 1996, 31: 309-318. DOI: 10.1016/s0065-7743(08)60470-4.Peer-Reviewed Original ResearchSolid-phase synthesisSolid supportFunctional group titrationCarbon-heteroatom bondsCompound structureCarbon-carbon bondsNew support materialDifferent analytical techniquesSmall molecule librariesSolid-phase reactionPrivileged structuresDiscrete compoundsLibrary synthesisMulticomponent reactionPhase synthesisParallel synthesisReaction conditionsBiological evaluationSynthesis sequenceFunctional groupsSupport materialLead optimizationCombinatorial librariesAnalytical techniquesLibrary design
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